Twitter allows you to send and receive tweets from their web-based interface at Twitter.com. However, if you cannot afford to check the website every now and then for new tweets, it might be time for you to choose a Twitter client which will do the job. Below, we’ve selected more than 20 application, which gives you access to the Twitter service without accessing Twitter.com. If you have a Twitter account, follow me too!
video preview of Seesmic Desktop here.
The first thing I noted about Birdfeed is that it has a very clean, slick user interface. Birdfeed also has local caching. It remembers you timeline when you are offline and catches up when you get back online. With Birdfeed, reply to tweets goes SMS style. It treats tweets as SMS and allows you to reply to them easily. You also get notifications of unread tweets and more.
CNET’s review of both of them here.
Mobile Twitter Clients
do loads more! Check out their website for more features, the list is simply too long.